Using the animated image of the famous chemist Mendeleev as a series, it leads the audience to understand the history of element discovery; understand the most important elements of hydrogen, oxygen, carbon and nitrogen for the universe and us; appreciate the power of toxic elements and their functions; the most active elements and the properties of the least active metals and non-metals; and the stories of carbon, silicon, uranium, iron and other elements that play a key role in the process of human civilization. Through interesting knowledge introductions, we will popularize the basic knowledge of chemistry to the Chinese audience and improve the scientific literacy of the whole people.