What would it be like to have ESP? Having the ability to know what is happening elsewhere and the power to do something about it must be so convenient! But, for normal eighth-grader Mami Sakura, suddenly having a sixth sense awakened is akin to disaster. Whenever someone needs help, Mami hears bells ringing inside her head. She is an "ESPer," and when trouble calls, whether she is on a date or in the middle of dance practice, her sense of justice forces her to rush to the rescue. Through the adventures of this cute and diligent "ESPer," viewers will realize that helping someone close at hand is the first step to helping the whole world.