In the year 2098, Los Angeles Police Department detective Hammond (Michael Jai White) and his new partner "Andy" (Randy Wayne) — a state of the art crimefighting robot cop — are tasked with recovering a runaway Telepresence android containing the consciousness of Mayor Jacobs's (Charles S. Dutton) daughter Helen (Larissa Vereza), who remains unaware that she is a human mind in a machine body. Hammond does not trust machines due to a prior incident in which his partner was killed by an automated gun turret despite their using a code to control it, and maintains a tense, often sarcastic relationship with Andy. Hammond and Andy are dispatched to the "Zone," a quarantined section of Los Angeles devastated by an earthquake and subsequent nuclear leaks, which have infected and mutated the Zone's residents.