The cartoon starts when all the furniture was thrown out and Jerry Mouse is chased off the house by Tom Cat and Spike and Tyke (characters). The mouse gets an iron pipe (fluid conveyance), the cat gets a frying pan and the dog gets a baseball bat. They start to fight about, but Spike all of a sudden stops it. He questions, "What's all this fighting getting in us, huh? Cats can get along dogs, can't they? And mice can get along with cats, can't they?" The three characters decide to become pals, and they sign a peace treaty in the house.