Wealthy, vain New York City businessman Karl Brussard (George Coulouris) is behaving oddly - answering telephones that aren't ringing, forgetting that he owns ships in Miami, failing to recognise his own physician, Dr Charot (William Sherwood). Charot shows Brussard an x-ray of his head. Brussard looks at it admiringly and says, 'Ah, beautiful - the brain of Karl Brussard!' But Charot tells him that he has an inoperable brain tumour and advises him to go to England, where Dr Phil Merrit (Robert Hutton (actor)) is researching brain transplantation. Brussard and his much younger companion, Odette Vernet (Nadja Regin), leave at once.