Mary Stevens (Kay Francis) and her old friend Don Andrews (Lyle Talbot) find themselves graduating from medical school at the same time. They decide to set up their respective medical offices in the same building. Mary builds her reputation despite many patients refusing to be treated by a woman. Don, however, begins dating Lois Cavanaugh (Thelma Todd), whose family is rich and influential, and neglects his practice for the privileges of a social life.