Two Lost in a Dirty Night follows two Brazilian illegal immigrants living in New York City, United States. Paco, a tomboy whose real name is Rita, is very aggressive, strange and mysterious. Antônio, nicknamed Tonho, wants to return to Brazil, because he had no success living in America. They live in a kind of loft. They met each other while Paco was acting as a male prostitute, doing a blowjob on a man. Then, he discovers that Paco is a girl and became furious, trying later to rape her. Tonho saves her and invites her to live with him.