Set in Cape Town, South Africa, Mama Jack is the story of Jack Theron, an ordinary person working on a film set as a grip. However, his movie producer boss, John Daragon, hates him and wants to remove him from the production of the movie they are producing about Nelson Mandela, ''Sweet Bird of Freedom''. In a bid to get rid of Jack, the producer spikes his drink with a fictitious drug, Mama Africa, at a glamorous function, and before long Jack has unwittingly offended all the attending dignitaries, ruined the function and got himself on the wrong side of the law while hallucinating.