Death Race owner R.H. Weyland has been forced to sell the rights to Niles York, a British billionaire who acquired the rights by hostile takeover. York intends to relocate the Death Race to South Africa as the Transcontinental Death Race. Before leaving, Weyland arranges Carl Lucas, also known as Frankenstein (Death Race), to have surgery to heal the infected and deadly scars on his face sustained in Death Race 2. With Lucas one win away from gaining his freedom, York threatens to kill him if he wins.