Jon Arbuckle becomes concerned about Garfield (character)'s behavior after he and Odie mess up his house. While Jon tries to take him to the veterinarian, Garfield accidentally falls out from Jon's car and later becomes lost in downtown. Garfield soon runs into a large gang of unfriendly alley cats known as the Claws. After antagonizing their leader, Garfield flees into an abandoned Italian restaurant, where he is reunited with his long lost mother. The building was Garfield's birthplace and where he discovered his love for lasagna. Meanwhile, Jon calls Garfield's vet, Dr. Liz Wilson, to tell her about Garfield's disappearance, but Liz hangs up on Jon instead.