Dante, a demon hunter, runs an agency called "Devil May Cry". He is hired to protect Patty Lowell, a young orphan who has just inherited her late father’s entire estate. While Patty searches for her mother, her relatives—and demons—are trying to kill her to seize the inheritance meant for her. As if that weren’t enough, the demons are also after a mysterious necklace the helpless girl is wearing. What could be so important about this jewel?