The story tells of the fictional Kingdom Hospital located in Lewiston, Maine, built on the site of a mill that manufactured military uniforms during the American Civil War. Previously, a hospital known as the "Old Kingdom" had been built on the site, but it burned down. The current hospital is known as the "New Kingdom". The hospital's "turbulent" nature seems to reflect its ominous logo, a crimson stylized dagger, predicting what will come.