The series follows the adventures of a team of scientists on the Calico, a hydrofoil research vessel, headed by Captain Carl Majors. The rest of the crew include scientist Dr. Quinn Darien, her nephew Pete Darien and her research assistant Brock Borden. Also along for the ride is Godzooky, the "cowardly nephew" of Godzilla and Pete's best friend, in a comic foil role in the show. The group often call upon Godzilla by using a special signaller when in danger, such as attacks by other giant monsters.